Technical Debt (TD) is a phenomenon that represents technical decisions about “shortcuts” and “workarounds” taken during software development associated with internal quality activities. TD is an almost inevitable phenomenon in all software projects, negatively or positively impacting the all-project ecosystem, mainly maintenance and evolution activities. The investigations undertaken in this doctoral research allow us to identify that, despite the relevance of this topic in the software industry, its understanding and management are still incipient, mainly in software organizations. Based on our findings, we proposed an evidence-based framework (isTDM) to support software engineers in managing TD in their projects. The proposed framework comprises three technologies: a set of guidelines (TDM Guidelines), a Glossary of Terms on TDM, and a Portfolio of TDM Technologies. These three instruments can be used together or separately. In addition, a computational infrastructure was structured to make available and enable the use of developed technologies that comprise isTDM. Finally, a study was performed with software engineers to evaluate the TDM Guidelines' feasibility. This thesis also provides a knowledge body on TD and its management in software projects that can be used to guide future research and to support internal quality management in software projects.